0000014644 00000 n
0000236616 00000 n
0000368887 00000 n
0000014615 00000 n
0000090304 00000 n
Seung-Hwa Baek, Morris Srebnik and Raphael Mechoulam* Hebrew University Pharmacy School, Jerusalem 91120, Israel. 0000364364 00000 n
0000121507 00000 n
%%EOF
0000369641 00000 n
0000368139 00000 n
0000413595 00000 n
0000016641 00000 n
0000382153 00000 n
0000016361 00000 n
0000407844 00000 n
startxref
0000364260 00000 n
BF3 should be the most recommendable acid at the cyclization/cleavage reaction for amino acid sequence and configuration determination of peptides containing D-amino acid residues. 0000397165 00000 n
0000306932 00000 n
0000316039 00000 n
0000412919 00000 n
{J�W���;݂����ZT����-���b�zC}=+ŋǖt��{ʆoqi���s"�W����`a�F�l�0�)�l�L���mT���X�s��i��3�'ɒ��2�q�Cm!I���!�~�\"?W�V\��3�H���۳8%Y�T��5[lW����{j���~���&ٶ���/�7�]��J朽����Λ��8���g$Ƈ2���l�44Tq/}r��]:���L�v�tV� 7G�u�,���j�|m�2����2��嫝g���/v\������M��=ݷ^||�W�er[���%'}�3��֜�Ĝy��4����j]wڲ,Z���F�Y����2��H��>��{kwZMl�caw�#5��z�+z��ƅ�����xm�����z�P[heu�����x�n =�^��A��Ȓy��Pӫ;�][u
�=����$���
u*��˔��]V�Ě�gW䅏2����DGG�(��bL��r�ӕ��q;��ʗd`c��/M�r��/�e�9���ٓ��Iſ3ڋ:��)�S�͔�~ܼ���M��!\����MS}� ����;����A�� rClj�H��@7x��(V�p�3`� *j*��~Op+��������C3�Q":�ܡu�=�|�`�J�ÂW���ʯ��?y���Iٺx�q�h �\(H�4�>x�4�Ɉ���4TM�GSPb�R�I1�� ��bX��3䒽0�ѕ��R_�v�h(YD6��h-��!@a��9��f%=��6�;��q��SעB�t��h�Gۦ5�8��. 0000367820 00000 n
0000010502 00000 n
0000367226 00000 n
0000013304 00000 n
By continuing you agree to the use of cookies. 0000366900 00000 n
AN IMPROVED SYNTHESIS OF CANNABIDIOL. These organic reactions are frequently employed to achieve the synthesis of natural products. 2001 Aug;15(5):319-27. doi: 10.1002/bmc.80. 0000015134 00000 n
0000397589 00000 n
0000005978 00000 n
0000316349 00000 n
0000007307 00000 n
0000309756 00000 n
Aldrich - 295027; Boron trifluoride ≥99.5%; CAS No. 0000133499 00000 n
0000064269 00000 n
Proton: a major factor for the racemization and the dehydration at the cyclization/cleavage stage in the Edman sequencing method. 0000394534 00000 n
0000091322 00000 n
0000089521 00000 n
0000089129 00000 n
0000365934 00000 n
0000370139 00000 n
1845 0 obj
<>
endobj
0000012680 00000 n
0000012919 00000 n
0000379222 00000 n
0000313307 00000 n
0000007798 00000 n
0000367117 00000 n
0000364796 00000 n
0000380126 00000 n
Boron trifluoride-etherate (Lewis acid) as an efficient acid at cyclization/cleavage reaction of D/L-amino acids affording the retention of their original configuration in the Edman sequencing method of peptides. 10.1002/(SICI)1099-0801(199603)10:2<95::AID-BMC557>3.0.CO;2-H. A novel method for the amino acid sequence/configuration determination of peptides containing D/L-amino acids utilizing a fluorogenic Edman reagent, 7-N,N-dimethylaminosulphonyl-4-(2,1,3-benzoxadiazolyl)isothiocyanate (DBD-NCS). 0000016670 00000 n
Abstract: Boron trifluoride … 0000386881 00000 n
0000366792 00000 n
0000209558 00000 n
0000007941 00000 n
Atomic number of boron is 5 and its electronic configuration is 2, 3. 0000010168 00000 n
0000111001 00000 n
Get the latest public health information from CDC: https://www.coronavirus.gov. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 0000364904 00000 n
0000307274 00000 n
0000310037 00000 n
0000309029 00000 n
Please enable it to take advantage of the complete set of features! 0000013024 00000 n
Boron trifluoride-etherate (BF3), one of the Lewis acids, was found to be an efficient acid in the Edman sequencing method, affording the retention of the N-terminal amino acid configuration at the cyclization/cleavage reaction from peptides. NLM Amino acid sequence and D/L-configuration determination methods for D-amino acid-containing peptides in living organisms. 0000369837 00000 n
To accomplish the hydroxylation of double bond, cleavage of epoxides, esterification of acids and many cyclization reaction boron trifluoride etherate proved very useful compared to other Lewis acids. 0000008881 00000 n
0000163372 00000 n
0000364472 00000 n
0000392907 00000 n
0000387119 00000 n
0000414185 00000 n
0000393374 00000 n
0000366364 00000 n
Get the latest research from NIH: https://www.nih.gov/coronavirus. 0000370334 00000 n
MODIFIED LEWIS ACID REAGENT. [� �R�mDm� �&}����@w?RC������Fs>C22�����b,���0�$�Ht����FE$:��H6��d������1����|O˱(��֗��l�.=�ϋc�g���1+��XM�ː��5�u����d����\���U�.y��\w-�����>`U�5��xVI��]X�f�[I�����?q?�P-K ����@���(m��o{o��*�z���2�o�����|�5�ߧ4�ˮu�/�sJd�wlx`���s������-�6�_#�Lj8. 0000367924 00000 n
0000364580 00000 n
0000371216 00000 n
0000369482 00000 n
0000089969 00000 n
0000411153 00000 n
0000120923 00000 n
We use cookies to help provide and enhance our service and tailor content and ads. Detection of DBD-carbamoyl amino acids in amino acid sequence and D/L configuration determination of peptides with fluorogenic Edman reagent 7-[(N,N-dimethylamino)sulfonyl]-2,1,3-benzoxadiazol-4-yl isothiocyanate. <<60F45142631C2C46BA401530CAE6E95E>]/Prev 607289/XRefStm 5761>>
0000316741 00000 n
0000005761 00000 n
0000249108 00000 n
0000310304 00000 n
0000368032 00000 n
0000242859 00000 n
0000163843 00000 n
0000091692 00000 n
0000007653 00000 n
Chemical Identity 0000028443 00000 n
xref
HHS 0000334776 00000 n
Clipboard, Search History, and several other advanced features are temporarily unavailable. Even after 30 min of the cyclization/cleavage reaction at 50 degrees C, DBD-TZ-amino acids retained their configuration to the same degree. 0000385213 00000 n
2023 0 obj
<>stream
0000368780 00000 n
0000012421 00000 n
OF CANNABIDIOL. 0000134356 00000 n
trailer
1845 179
0000368564 00000 n
and … 0000370238 00000 n
hެ�T�U����6`�:3�p�� 0000415700 00000 n
0000006161 00000 n
0000009243 00000 n
0000366471 00000 n
0000406004 00000 n
0000015163 00000 n
0000365826 00000 n
0000121403 00000 n
0000110828 00000 n
0000000016 00000 n
0000313773 00000 n
0000306423 00000 n
0000370040 00000 n
0000008614 00000 n
Copyright © 2020 Elsevier B.V. or its licensors or contributors. 0000012866 00000 n
0000133773 00000 n
Hence by sharing 1 electron with each fluorine atom, boron has 3 sigma bonds around it. 0000017953 00000 n
This pungent toxic gas forms white fumes in moist air; it is a useful Lewis acid and a versatile building block for other boron compounds.